The PPP1R12B Antibody - Middle region from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human antigen. The PPP1R12B Antibody - Middle region has been validated for the following applications: Western Blot.
Description
This is a rabbit polyclonal antibody against MYPT2. It was validated on Western Blot
Target Description: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome